Showing posts tagged with: anti-cancer
Cancer 'Smart Bomb' Successfully Tested in US
Scientists have successfully tested a capillary "smart bomb" that simultaneously attacks cancer and boosts the immune system.
The tiny hollow spheres become trapped in leaky tumour blood vessels, where they unleash an anti-cancer drug.
At the same time the spheres, called nanolipogels (NLGs), release a protein that rallies the body's own defences.
Researchers tested the spheres in mice on melanoma skin cancer that had spread to the lungs.
Tumour growth was significantly delayed and the survival of the mice increased.
The new technology overcomes a problem with cancer treatment that has been difficult to tackle using conventional therapies, say the scientists.
Cancer tumours are known to secrete chemicals that confuse the immune system.
But attempts to boost patient immunity while at the same time neutralising the cancer's chemical arsenal rarely work.
The NLGs, described in the journal Nature Materials, package together two completely different kinds of molecule.
One is designed to overcome a potent cancer defence weapon called TGF-beta, which stunts the local immune system.
The other, an interleukin signalling molecule, boosts immune system activity.
Researcher Dr Stephen Wrzesinski, from Yale University School of Medicine in the US, said: "One problem with current metastatic (spreading) melanoma immunotherapies is the difficulty managing autoimmune toxicities when the treatment agents are administered throughout the body.
"The novel nanolipogel delivery system we used will hopefully bypass systemic toxicities while providing support to enable the body to fight off the tumour at the tumour bed itself."
Each NLG is small enough to travel through the bloodstream, but large enough to get entrapped in leaky cancer blood vessels. Once trapped, they biodegrade to release their cargo.
Article taken from Sky News - click here to view.
Breast cancer drug tamoxifen recommended for 'high risk' women
Women in England and Wales with a strong family history of breast cancer could be offered medication on the NHS to try to prevent the disease.
The National Institute of Health and Clinical Excellence has launched a consultation on whether tamoxifen could be given for up to five years.
If approved later this year, the draft guidelines would be the first of their kind in the UK.
Charity Breakthrough Breast Cancer welcomed the "exciting, historic step".
To read the full article click here.
- Jun 2021 (1)
- Feb 2020 (1)
- Apr 2018 (1)
- Mar 2018 (1)
- Jan 2018 (3)
- Dec 2017 (5)
- Nov 2017 (7)
- Oct 2017 (8)
- Sep 2017 (8)
- Aug 2017 (4)
- Jul 2017 (5)
- Jun 2017 (5)
- May 2017 (3)
- Apr 2017 (3)
- Mar 2017 (4)
- Feb 2017 (2)
- Jan 2017 (1)
- Dec 2016 (5)
- Nov 2016 (8)
- Oct 2016 (7)
- Sep 2016 (2)
- Aug 2016 (6)
- Jul 2016 (6)
- Jun 2016 (1)
- A Career in Care - Jessica's Story
- Routes Blog 2020!
- Liverpool CQC inspection achieves a Good
- A huge THANK YOU to all our fantastic field and branch staff!
- Recruitment Opportunity in Newcastle
- Preston has moved
- Tameside's Christmas Toy Collection
- Certificate of Inspiration
- Tameside receive an OUTSTANDING in Care
Most Popular Posts
- Healthcare Assistants wanted in Blackpool to care for a gentleman and lady with spinal injuries
- Mental Health campaign receives additional funding
- Routes Healthcare need experienced childminders across the North West of England
- Accounts & Payroll Trainee Vacancy Routes Healthcare - Macclesfield
- Social Worker Struck Off
- Routes Healthcare Blackpool is committed to the modern apprenticeship scheme
- Routes Childcare - The local company with the Worldwide experience!
- Cancer 'Smart Bomb' Successfully Tested in US
- Personalisation 'at high risk of failure', Norman Lamb told